Personal Info
- Country of residence: Jordan
Information
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 1
- A yma n A . Z a y e d , M.D. , M. S c . , F . A . C .E . , F . A . C . P .
School of Medicine/Jordan University Hospital
The University of Jordan
P.O.Box 13046
Amman 11942 , Jordan.
Telephone: 962797224442, 962798504465 Email: baraaayman@gmail.com
Personal
Born December 28, 1964
Married, with five children.
Interests include chess playing, poetry, and reading.
Nationality: *Jordanian
*USA
Current Position
Sep 2013 – Present Associate Professor
Chief, Division of Endocrinology, Diabetes and Metabolism
Department of Internal Medicine
School of Medicine/Jordan University Hospital
The University of Jordan
Amman - Jordan
March 2008 – Sep 2013 Assistant Professor
Chief, Division of Endocrinology, Diabetes and Metabolism
Department of Internal Medicine
School of Medicine/Jordan University Hospital
The University of Jordan
Amman - Jordan
Prior Appointments
Oct 1998 – Oct 2000 Chairman
Department of Internal Medicine
Northeast Alabama Regional Medical Center
Anniston, Alabama
U.S.A
Oct 2000 – Oct 2002 Representative
Department of Internal Medicine
Northeast Alabama Regional Medical Center (NEARMC)
Anniston, Alabama
U.S.A
Academic/Teaching Experience
Sep 2013 – Present Associate Professor
Chief, Division of Endocrinology, Diabetes and Metabolism
Department of Internal Medicine
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 2
School of Medicine/Jordan University Hospital
The University of Jordan
Amman – Jordan
March 2008 – Sep 2013 Assistant Professor
Chief, Division of Endocrinology, Diabetes and Metabolism
Department of Internal Medicine
School of Medicine/Jordan University Hospital
The University of Jordan
Amman, Jordan
November 1996 – April 2006 Clinical Assistant Professor
Division of Endocrinology, Diabetes, and Metabolism
Department of Internal Medicine
School of Medicine
University of Alabama at Birmingham
Birmingham, Alabama
U.S.A
July 1994 – Dec 1995 Lecturer, Endocrinology Didactic Lectures
Internal Medicine Residency Program
University of Alabama at Birmingham
Birmingham, Alabama
U.S.A
Jan 1995 – June 1995 Lecturer, Endocrinology Teaching Course
Internal Medicine Residency Program
University of Alabama at Birmingham
Baptist Medical Center
Montgomery, Alabama
U.S.A
May 1995 Clinical Instructor
Correlative Endocrine Pathology Course for 1994-1995
University of Alabama at Birmingham
School of Medicine
Birmingham, Alabama
U.S.A
Octr 1994 – April 1995 Preceptor, Introduction to Clinical Medicine
University of Alabama at Birmingham
School of Medicine
Birmingham, Alabama
Other Academic Experience
June 2013 – present Examiner
Internal Medicine Examination Committee
Arab Medical Council
Amman – Jordan
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 3
Feb 2013 – present Examiner
Endocrinology, Diabetes and Metabolism Committee
Jordanian Medical Council
Amman – Jordan
2004 Reviewer
Endocrinology, Diabetes and Metabolism Questions
American Board of Internal Medicine
Current Teaching Load
2008 – present Lecturer, Endocrinology Didactic Lectures
Fourth and Sixth Medical Students
Internal Medicine Department
School of Medicine
The University of Jordan
Amman – Jordan
2008 – present Clinical Training
Fourth and Sixth Medical Students
Internal Medicine Department
School of Medicine/ Jordan University Hospital
The University of Jordan
2008 – present Post Graduate Clinical Training
Internal Medicine Residency Program
Post Graduate School
The University of Jordan
Medical Education
1986 – 1989 The University of Jordan, School of Graduate Studies
Amman, Jordan
Master’s Degree in Medical Sciences
1979 – 1985 The University of Jordan, School of Medicine
Amman, Jordan
Bachelors of Medicine and Surgery, “M.D.”
Post Graduate Education/Training
July 1993 – Dec. 1995 The University of Alabama at Birmingham
Birmingham, Alabama
USA
Fellow, Division of Endocrinology & Metabolism
Program Directors: Robert A. Kriesberg, M.D.
Jeffrey Kudlow, M.D.
June 1991 – June 1993 The University of Massachusetts Program in Internal Medicine
Medical Center of Central Massachusetts
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 4
Worchester, Massachusetts
USA
Resident in Internal Medicine
Program Director: Ann Errichetti, M.D.
July 1985 – July 1989 Jordan University Program in Internal Medicine
University Hospital
Amman, Jordan
Intern and Resident in Internal Medicine
Program Director: Abdallah Abbadi, M.D.
Certification and Recertification
1995 (No. 149098) Diplomat, American Board of Endocrinology, Diabetes and
Metabolism (1st attempt)
2005 Recertified, Diplomat American Board of Internal Medicine (1st
attempt)
1993 (No. 149098) Diplomat, American Board of Internal Medicine (1st attempt)
1989 Master’s Degree in Medical Sciences “M.Sc.” (1st attempt)
1985 Bachelor of Medicine and Surgery “M.D.” (1st attempt)
1979 National Jordanian Education Matriculate (1st attempt)
Work Experience
March 2008 – Present Chief and Consultant in Endocrinology, Diabetes and
Metabolism
School of Medicine/Jordan University Hospital
The University of Jordan
Amman – Jordan
April 2006 – March 2008 Consultant Endocrinologist.
King Fahd Armed Forces Hospital
Jeddah, Saudi Arabia
Feb1996 – April 2006 Internist/Endocrinologist, Anniston Medical Clinic
Staff Physician, Department of Internal Medicine/Endocrinology
Northeast Alabama Regional Medical Center, and String fellow
Memorial Hospital
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 5
Anniston, Alabama
USA
Nov 1989 – April 1991 Senior Medical Resident, Security Forces Hospital. Riyadh, Saudi
Arabia
July 1986 – Nov 1989 Medical Resident, Jordan University Hospital. Amman, Jordan
Memberships and Fellowships
July 2013- Present Jordan Chapter- AACE
2000- Present Fellow, American College of Endocrinology – F.A.C.E.
Nov1997- Present Fellow, American College of Physicians/American Society of Internal
Medicine – F.A.C.P.
1994- Present American Association of Clinical Endocrinologists (AACE)
1986- Present Jordanian Medical Association
Institutional and Committee Memberships
Jan 2015-present Credential Committee
Jordan University Hospital
Amman, Jordan
Jan 2015-present Institutional Review Board (IRB)
Jordan University Hospital
Amman, Jordan
Sept 2014-present Scientific Research Council Committee
Jordan University Hospital
Amman, Jordan
June 2013-Present Internal Medicine Examination Committee
Arab Medical Council
Amman, Jordan
Feb2013-Present Endocrinology and Diabetes Scientific and Examination
Committee
Jordanian Medical Council.
Amman, Jordan
Aug2012- Present Medical Record Committee
Jordan University Hospital.
Amman, Jordan
Jan2010- Present Endocrinology and Diabetes Committee
Representative of The University of Jordan
Jordanian FDA
Amman, Jordan
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 6
Jan2010- Present Endocrinology and Diabetes Tenders Committee
Jordan University Hospital
Amman, Jordan
Jan2009- Present Endocrinology and Diabetes Committee
Representative of The University of Jordan
Joint Procurement Department
Amman, Jordan
2009 Medical Students Clinical Training Committee
School of Medicine
The University of Jordan
Amman, Jordan
2008 Former Medical Graduates Committee
School of Medicine
The University of Jordan
Amman, Jordan
Oct 1998 – Sep 2002 Executive Committee
Northeast Alabama Regional Medical Center
Anniston, Alabama
USA
Feb 1996 – Feb 2002 Education Committee
String fellow Memorial Hospital
Anniston, Alabama
USA
Community Activities
2010 Public Health Campaign
Medical Students/ School of Medicine
The University of Jordan
Amman, Jordan
1997 – 2006 Educational Lectures in Diabetes Mellitus (for Diabetic patients)
Anniston, Alabama
USA
1997 – 2006 Education Lectures in Diabetes Mellitus (for Diabetic patients)
Heflin, Alabama
USA
1994 Instructor, Camp Seale Harris – Camp for Diabetic Children
Alexandria City, Alabama
USA
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 7
Presentations
March 2015 Poster Presentation
The Emerging role of Serum IGF-I/IGFBP-3 ratio in the Diagnosis of
Children with Growth Hormone Deficiency .
Ayman A. Zayed , et al.
ENDO 2015 - The Endocrine Society’s 97th Annual Meeting & Expo
Convention Center -San Diego, CA, March 6th, 2015
USA
June 2014 Poster Presentation
Is Hashimoto’s Thyroiditis a Risk Factor for Medullary Thyroid
Carcinoma ? Our Experience and a Literature Review.
Ayman A. Zayed, Moaath K. Mustafa Ali, Omar M. Jaber, et al.
The Endocrine Society’s 97th Annual Meeting and Expo.
Chicago, Il
USA
Jun2013 Poster Presentation
Predetermined Anti-diabetic drug regimen adjustments during
Ramadan fasting: Evaluation of safety.
Ayman A.Zayed, Awni Shahait, Hamzah Zeidan, Munther Momani
and Al-Motassem Yousef.
The Endocrine Society’s 96th Annual Meeting and Expo.
San Francisco, CA
USA
Jun 2013 Poster Presentation
Multiple Osteolytic lesions, Café-au-lait spots, axillary freckling with
Pseudoacromegaly: A new syndrome?
Munther Momani, M. H. Ramzown and Ayman A. Zayed
The Endocrine Society’s 96th Annual Meeting and Expo.
San Francisco, CA
USA
2009 Invited Faculty
Internal Medicine Board Review Course
King Hussain Cancer Centre (KHCC)
Amman, Jordan
2008 Invited Faculty
Internal Medicine Board Review Course
King Hussain Cancer Centre (KHCC)
Amman, Jordan
April 2007 Invited Faculty
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 8
King Faisal Specialist Hospital Internal Medicine Board Review course
for Arab and Saudi Board.
Jeddah, Saudi Arabia
April 2006 Invited Faculty
King Faisal Specialist Hospital Internal Medicine Board Review course
for Arab and Saudi Board.
Jeddah, Saudi Arabia
Oct 1997 Invited Speaker
“Glucocorticoid remediable Aldosteronism” Endocrine Grand Rounds
Emory University.
Atlanta, Georgia
USA
Conferences (Too Many to Count).
Special Skills in Endocrinology
Fine Needle Thyroid Biopsy
Thyroid Ultrasound
Licensed to Perform Radioactive Iodine Therapy
Bone Densitometry
Licensure
1993 State of Alabama (18652)
1986 Jordan
Research Affiliations
9/1999 – April 2006 Clinical Investigator
Pinnacle Research Group, LLC
Anniston, Alabama
USA
Book Chapters and Publications
Zayed A.A., Stock J.L., Liepman M., Wollin M., Longcope C. “Feminization as a Result of Both
Peripheral Conversion of Androgens and Direct Estrogen Production from an Adrenocortical
Carcinoma.” J Endo Inv. 17:275-278. 1994
Zayed A.A., Frank S.J., Diabetes and Metabolism. In Cooper J.A., Pappas P.G. (eds): Cecil Review of
General Internal Medicine. 6th Edition, Philadelphia. W.B. Saunders Company. 1996 (book chapter)
Hayne V., Zayed A.A., Endocrine/Reproductive and Calcium and Bone Diseases. In Cooper J.A.,
Pappas P.G. (eds): Cecil Review of General Internal Medicine. 6th Edition, Philadelphia. W.B. Saunders
Company. 1996 (book chapter)
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 9
Pittman C.S., Zayed A.A., Myxedema Coma. In Bardin CW (ed): Current Therapy in Endocrinology and
Metabolism. 6th Edition. St. Louis, Mosby Year Book, Inc. 1997 (book chapter)
Al-Amer R.M, Sobeh M.M., Zayed A.A, Al-domi H.A. “Depression among adults with Diabetes in
Jordan: Rosk factors and relationship to blood sugar control” Journal of Diabetes and its Complications
25:247-252,2011.
Zayed A.A., Shahait A.D., Ayoub M.N., Yousef A. “Smokers’ hair: Does smoking cause premature
hair graying?” Indian Dermatology Online Journal 4:90-92 , 2013 .
Zayed A.A., Alzubaidi M, Atallah S, Momani M, Al-Delaimy W, “ Should Food Intake and Circadian
Rhythm be Considered When Measuring Serum Calcitonin Level ? “ Endocrine Practice 19(No.4):620 –
629,2013 .
Zayed A. A., Shahait A. D., Zeidan H., Momani M., Yousef A., “Predetermined Anti-diabetic drug
regimen adjustments during Ramadan fasting: Evaluation of safety.” [ Abstract], Endocr rev, Vol.34
(03_Meeting Abstracts): SUN-830
Momani M., Ramzown M. H., Zayed A. A., “Multiple Osteolytic lesions, Café-au-lait spots, axillary
freckling with Pseudoacromegaly: A new syndrome?” [ Abstract], Endocr rev, Vol.34 (03_Meeting
Abstracts): MON-307.
Zayed A. A., Mustafa Ali M., Momani M., “The Prevalence of Growth Hormone Deficiency among
Children of Short Stature in Jordan and its Relation to Consanguinity.” [ Abstract], Endocr rev, Vol.34
(03_Meeting Abstracts): SUN-641
Al-Taee M. A., Zayed A. A., Abood S. N., Al-Ani M. A., Al-taee A. M., Hassani H. A., “Mobile-
Based Interpreter of Arterial Blood Gases Using Knowledge-Based Expert System” International Journal
of Pervasive Computing and Communications Vol. 9 No.3: 270 – 288,2013 .
Zayed A.A, Mustafa MK, Al-Ani MA, et al. “The Prevalence of Isolated Growth Hormone
Deficiency among Children of Short Stature in Jordan and its Relationship with Consanguinity”
Clinical Endocrinology (2014)
Zayed A.A, Mustafa MK, Jaber OM, et al. “Is Hashimoto’s Thyroiditis a Risk Factor for Medullary
Thyroid Carcinoma ? Our Experience and a Literature Review.” Endocrine (2014)
Zayed A.A, et al. “The Emerging role of Serum IGF-I/IGFBP-3 ratio in the Diagnosis of Children
with Growth Hormone Deficiency.” Submitted .
Momani, Munther S., Ayman A. Zayed, & Faris G. Bakri. "Subacute thyroiditis following
influenza vaccine: a case report and literature review." Italian Journal of Medicine[Online], 9.3
(2015): n. pag. Web. 23 Jul. 2015.
Y.G. Al hasan;M.A. Zmaili; V.Dabravolskaite; A.A. Zayed, “Diabetes Mellitus and
Cardiovascular Disease”, in Complex Cardiac, Management of Multi Organ System Dysfunction,
ed. by Omar M. Lattouf, et al. e-book,2016.
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 10
Research
Co-Investigator (site) - SmithKline Beecham Protocol 265805/014. (1999)
P.R.O.T.E.C.T. Study. Precose: Resolution of Optimal Titration to Enhance Current Therapies.
A Double-Blind, Multicentre, Parallel Group Study to Compare the Efficacy and Safety of oral SB-
265805 320mg Once Daily Versus oral Levafloxin 250mg Once Daily for 10 Days in the Treatment of
Pyleonephritis or Complicated Urinary Tract Infections (UTI).
Principal-Investigator (site) - Glaxo Wellcome Protocol PPA30003. (1999)
A Multicenter, Randomized, Double-Blinded, Parallel-Group, Placebo-Controlled, Clinical Evaluation
of {Oral GI262570} Sodium Tablets (2.5, 5.0, and 7.5 mg) in Combination with Current Insulin
Therapy for 26 Weeks Duration in Subjects with Type 2 Diabetes Mellitus Who are Inadequately
Controlled with Insulin Alone.
Principal-Investigator (site) - R.W. Johnson Protocol TOPMAT-NP-003. (2000)
A Double-Blind, Placebo-Controlled, Parallel Group, Dose Response Study to Evaluate the Efficacy
and Safety of {Topiramate} Versus Placebo in the Relief of Pain in Diabetic Peripheral Neuropathy.
Principal-Investigator (site) -Glaxo-Wellcome Protocol PPA 30015. (2000)
A Multi-center, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Pilot Study of 3
Months Treatment of Oral {GI262570} 7.5 mg Once Daily, Pioglitazone 45 mg Once Daily, and
Rosiglitazone 4 mg Twice Daily on Postprandial Glucose following a SUSTACAL Meal Challenge in
Subjects with Type 2 Diabetes Mellitus.
Co-Investigator (site) - SmithKline Beecham Protocol BRL 49653/048. (2000-2005)
A Randomized, Double-blind Study to Compare the Durability of Glucose Lowering and Preservation
of Pancreatic Beta-Cell Function of {Rosiglitazone} Monotherapy Compared to {Metformin} or
{Glyburide/glibenclamide} in Patients with Drug-Naïve, Recently Diagnosed Type 2 Diabetes
Mellitus ( 2 years).
Co-Investigator (site) - Glaxo Wellcome Protocol PPA30016. (2000)
A Multi-Center, Randomized, Double-Blind, Parallel Group, Placebo-Controlled, Dose Ranging Study
to Assess the Efficacy and Safety of {GI262570 Sodium Tablets} (2.5 mg, 5 mg, and 7.5 mg)
Administered as a Daily Dose for 8 Weeks in Patients with Dyslipidemia.
Co Investigator (site) - Novartis Protocol COX 189A-114. (2000)
A 13-week multi-center randomized double-blind double-dummy placebo-controlled parallel group
trial of 2 doses of {COX189 (200 and 400 mg ad)} in patients with rheumatoid arthritis using
{celecoxib (200 mg bid)} as a comparator.
Co- Investigator (site) - Protocol CV138-055. Bristol-Myers Squibb. 2000-2001
A Randomized, Double Blind, Placebo Controlled Trial to Evaluate the Safety and Efficacy of
{Rosiglitazone} Added on to a Background of {Metformin/Glyburide} Tablets in Subjects with Type
2 Diabetes Mellitus Who have Inadequate Glycemic Control on {Metformin/Glyburide} Therapy.
Principal Investigator (site) - Bristol-Myers Squibb Protocol CV138-058. (2000)
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 11
A Multi-center, Randomized, Double-Blind, Active Control Trial to Compare the Safety and Efficacy
of A New Formulation of {Metformin/Glyburide} Tablets (500/1.25mg) to Metformin Monotherapy
as First Line Therapy in Patients with Type 2 Diabetes Mellitus who have Inadequate Glycemic
Control with Diet and Exercise.
Principal Investigator (site) - Bristol-Myers Squibb Protocol CV137-120. (2000)
Omapatrilat Cardiovascular Treatment Assessment Versus Enalapril (OCTAVE).
Co Investigator (site) - Novartis Protocols CHTF919/2201 & 2202. (2001)
A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding, Multi-center Study to Assess the
Efficacy, Safety and Tolerability of {tegaserod} Given Orally at Three Dose Levels (4mg, 12 mg, or
24mg) and Placebo in Patients with Functional Dyspepsia (FD) and Documented Normal/Delayed
Gastric Emptying.
Principal Investigator (site) - Bristol-Myers Squibb Protocol CV138-061. (2001)
A Multicenter, Randomized, Double-Blind, Clinical Trial Comparing The Safety And Efficacy Of
Metformin/Glyburide tablets to Metformin Plus Rosiglitazone Therapy In Patients With Type 2
Diabetes Mellitus Who Have Inadequate Glycemic Control With {Metformin} Monotherapy.
Co-Investigator (site) - Novartis Protocol CFOR258-F2302. (2001)
A 12-week randomized, multi-center, double-blind, double-dummy, placebo and active controlled,
parallel group study evaluating the safety and efficacy of Formoterol fumarate (10 μg b.i.d.) delivered
by the multi-dose dry powder inhaler (MDDPI) versus placebo versus albuterol pMDI q.i.d. in
patients with persistent asthma.
Principal Investigator (site) - Eli Lilly Protocol H6E-US-GLAI. (2001)
Pioglitazone versus Rosiglitazone in Subjects with Type 2 Diabetes Mellitus and Dyslipidemia.
A Multicenter, Stratified, Randomized, Double-Blind, Parallel-Group, Step-Up Comparison
Co-Investigator (site) - Glaxo-Wellcome Protocol SAS40027. (2001)
A Randomized, Double-Blind, Parallel Group, Comparative Trial of {Salmeterol/Fluticasone
Propionate} Combination Product {50/100mcg DISKUS Inhaler BID} versus {Fluticasone
Propionate 250mcg DISKUS Inhaler BID} in Adolescents and Adults with Moderate Persistent
Asthma.
Principal Investigator (site) - Astra Zenenca Protocol ZD4522IL/0065. (2001)
A 6-week, Open-Label, Dose-comparison Study to Evaluate the Safety and Efficacy of Rosuvastatin
versus Atorvastatin, Cerivastatin, Pravastatin and Simvastatin in subjects With Hypercholesterolemia.
Principal Investigator (site) - Bristol-Myers Squibb Protocol CV138-060. (2001)
A Double-Blind Randomized Study to Evaluate the Effects of Fixed Metformin/Glipizide therapy in
subjects with Type 2 Diabetes Mellitus who have inadequate glycemic control on half-maximum to
maximum of the labeled doses of Sulfonylurea monotherapy.
Co Investigator (site) - Novartis Protocol CCOX189-109. (2001)
A 13 week, international, multicenter, randomized, double-blind, double-dummy, placebo-controlled,
parallel group trial assessing the safety and efficacy of 2 doses {COX189 (200 mg and 400 mg od)} in
patients with knee primary osteoarthritis, using Celecoxib (200 mg od) as a comparator.
Principal Investigator (site) - Schwarz Protocol SP614. (2001)
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 12
A Randomized, Double-Blind Placebo Controlled Trial to Investigate Safety and Efficacy of {SPM
927} in Painful Diabetic Neuropathy.
Principal Investigator (site) - Restoragen Protocols BN02-C006 and C007. (2001)
A Study Comparing Safety and Efficacy of Three Doses of Recombinant Glucagon-like Peptide 1
(rGLP-1) (1.25 pmol/kg/min, 2.5 pmol/kg/min, and 5.0 pmol/kg/min) to Placebo Given by
Continuous Subcutaneous Infusion in Combination with Metformin and Sulfonylurea Over 12 Weeks
in Patients with Type 2 Diabetes Mellitus.
Principal Investigator (site) - Novartis Protocol CTRI476G2303. (2001)
Multicenter, double-blind, randomized, placebo-control, parallel-group study to evaluate the safety and
efficacy of three dose groups {Trileptal} in patients with neuropathic pain due to diabetic
neuropathy.
Principal Investigator (site) - Bristol-Myers Squibb Protocol CV168-006. (2001)
A Randomized, Double-Blind, Dose Ranging, Dose Comparison-Controlled Trial to Determine the
Safety and Efficacy of {BMS-298585} in Patients With Type 2 Diabetes.
Co- Investigator (site) - Solvay Protocol S2413006. (2002)
A Double-Blind, Placebo-Controlled, Randomized, Multicenter Study to Investigate the Safety and
Efficacy of 2 mg TID of Cilansetron Over 12 Weeks in Diarrhea-Predominant Irritable Bowel
Syndrome Subjects.
Sub Investigator (site) - Novartis Protocol CHTF919-2209. (2002)
A one-year open-label surveillance study to assess the long-term safety and tolerability of tegaserod (2
mg b.i.d. and/or 6 mg b.i.d.) in patients with symptoms of functional dyspepsia.
Principal Investigator (site) - Astra Zenenca Protocol ZD4522IL/0068. (2002)
An Open-label, Randomized, Multi-center, Phase IIIb, Parallel Group Switching Study to Compare
the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin with {Rosuvastatin} in
High Risk Subjects with Type IIa and IIb Hypercholesterolemia.
Principal Investigator (site) - Amylin Protocol AC2993-112. (2002)
A Phase 3, Randomized, Triple-Blind, Parallel-Group, Long-Term, Placebo-Controlled, Multicenter
Study to Examine the Effect on Glucose Control (HbA1c) of AC2993 Given Two Times a Day in
Subjects with Type 2 Diabetes Mellitus Treated With Metformin Alone.
Principal Investigator (site) - Amylin Protocol AC2993-113. (2002)
A Phase 3, Randomized, Triple-Blind, Parallel-Group, Long-Term, Placebo-Controlled, Multicenter
Study to Examine the Effect on Glucose Control (HbA1c) of AC2993 Given Two Times a Day in
Subjects with Type 2 Diabetes Mellitus Treated With a Sulfonylurea Alone.
Principal Investigator (site) - Amylin Protocol AC2993-115. (2002)
A Phase 3, Randomized, Triple-Blind, Parallel-Group, Long-Term, Placebo-Controlled, Multicenter
Study to Examine the Effect on Glucose Control (HbA1c) of AC2993 Given Twice Daily in Subjects
with Type 2 Diabetes Mellitus Treated With Metformin and a Sulfonylurea.
Sub Investigator (site) - BioCryst Protocol BC-01-03. (2002)
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 13
A Multicenter, Randomized, Double-Blinded Placebo-Controlled Study to Assess The Efficacy And
Safety Of {RWJ-270201} In The Treatment Of Acute Influenza A And B Infections In Healthy
Adults.
Principal Investigator (site) - Astra Zenenca Protocol ZD4522IL/0091. (2002)
A 48-Week Open-Label, Non-Comparative, Multicenter, Phase IIIb Study To Evaluate The Efficacy
and Safety of the Lipid-Regulating Agent {Rosuvastatin} in the Treatment of Subjects with
Fredrickson Type IIa and Type IIb Dyslipidemia, Including Heterozygous Familial
Hypercholesterolemia.
Sub Investigator(site) - Sepracor Protocol SC091-050. (2002)
A Double-Blind, Double-Dummy, Randomized, Placebo- and Active -Controlled, Multicenter,
Parallel-Group Study of {(R, R)-Formoterol} in the Treatment of Subjects with Chronic Obstructive
Pulmonary Disease.
Co- Investigator (site) - Pfizer Protocol A3191051. (2002)
Study of the efficacy and tolerability of once daily {Celebrex} and twice daily {naproxen} vs.
placebo in the treatment of African American subjects with osteoarthritis of the knee.
Co- Investigator (site) - Novartis Protocol COX109-117 and Protocol COX109-2332. (2002)
An international, multicenter, stratified, randomized, double-blind, double-dummy, parallel-group, 52-
week gastrointestinal clinical safety study to demonstrate that {COX189} (400 mg od) reduces the risk
to develop complicated ulcers as compared to {NSAIDS (naproxen 500 mg bid and ibuprofen 800 mg
tid)}, in osteoarthritis patients.
Co-Investigator (site) -Pfizer Protocol A3191052. (2002)
Study of the efficacy and tolerability of once daily {Celebrex} and twice daily {naproxen} vs.
placebo in the treatment of Asian American subjects with osteoarthritis of the knee.
Co-Investigator (site) - GlaxoSmithKline Protocol SMS40330. (2002)
A Randomized, Multi-Center, Cross-Over Comparison of Salmeterol Xinafoate Inhalation Powder
(50mcg BID) via the DISKUS and Salmeterol Xinafoate Inhalation Aerosol (42mcg BID) via the
Metered Dose Inhaler on Measures of Device Preference in Subjects with COPD.
Principal Investigator (site) - Bristol-Myers Squibb Protocol CV168018. (2003)
A Phase 3, Randomized, Double-blind, Placebo Controlled, Multicenter Trial to Evaluate the Safety
and Efficacy of {BMS-298585} as Monotherapy in Subjects with Type 2 Diabetes Who Have
Inadequate Glycemic Control.
Principal Investigator (site) - Bristol-Myers Squibb Protocol CV168022. (2003)
A Phase 3, Randomized, Double-blind, Placebo Controlled, Multicenter Trial to Evaluate the Safety
and Efficacy of {BMS-298585} as Monotherapy in Subjects with Type 2 Diabetes Who Have
Inadequate Glycemic Control on Metformin Alone.
Principal Investigator (site) -Protocol 01-02-TL-559-013 (2003)
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Efficacy of a
Combination of {TAK-559} and Glyburide Compared to Placebo and Glyburide in the Treatment of
Patients with Type 2 Diabetes Mellitus.
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 14
Principal Investigator (site) - Protocol 014-00. (2003)
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Dose-Range Finding Study of Once-
Daily Dosing of L-000224715 in Patients With Type 2 Diabetes Mellitus Who Have Inadequate
Glycemic Control.
Principal Investigator (site) - Protocol B3A20005. (2004)
A 12-Week, Parallel-Group, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to
Evaluate the Efficacy, Safety and Tolerability of GW427353B at 10 mg, 25 mg, 50 mg and 100 mg,
Administered Orally, Once Daily, as Monotherapy in Subjects With Type 2 Diabetes Mellitus.
Co-Investigator v - Protocol 712753/007/004 (2004)
A randomized, double-blind trial to evaluate the efficacy and safety of fixed dose Rosiglitazone
Metformin combination therapy compared to both Rosiglitazone and Metformin Monotherapy in
drug naïve type 2 diabetes mellitus subjects.
Principal Investigator (site) -Protocol SP742 (2004)
A Multi-center, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety
of {200, 400, and 600 mg/day of SPM 927} in Subjects with Painful Distal Diabetic Neuropathy
Principal Investigator (site) - Protocol IPT-2004-001 (2004)
An Open-Label, Randomized, 2-Way Crossover Study To Assess The Bioequivalence,
Pharmacokinetics, Pharmacodynamics, And Safety Of Single And Repeat Doses Of {Somatrem}
Compared With Protropin®
Principal Investigator (site) -Protocol SYR-322-002 (2004)
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Repeat-Dose Study to Determine the
Safety, Pharmacokinetic and Pharmacodynamic Effects and Efficacy of {SYR110322} in Patients with
Type 2 Diabetes Who are Either Newly Diagnosed or Managed with Diet and Exercise Alone for the
Past 3 Months
Principal Investigator (site) Protocol 01-02-TL-559-013 (2004)
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Efficacy of a
Combination of {TAK-559} and lyburide Compared to Placebo and Glyburide in the Treatment of
Patients with Type 2 Diabetes Mellitus.
Principal Investigator (site) Protocol 01-02-TL-559-014 (2004)
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Efficacy of
{TAK-559} in the Treatment of Patients with Type 2 Diabetes Mellitus.
Principal Investigator (site) Protocol SB275833/030 (2004)
Studies 030A and 030B: Two Identical Double-blind, Double-dummy, Multicenter, Comparative
Phase III Studies of the Safety and Efficacy of Topical 1% SB-275833, Applied Twice Daily, versus
Oral Cephalexin, 500 mg in Adults, or 12.5 mg/kg (250 mg/5 ml) in Children, Twice Daily, in the
Treatment of Uncomplicated Secondarily Infected Traumatic Lesions
Principal Investigator (site) Protocol # SK&F-105517/902 (2005)
A Randomized, Double-Blind, Placebo-Controlled, PK/PD Modeling, Multicenter Study to Compare
the β1-Blocking Effects of Carvedilol Phosphate MR Capsule Formulation to COREG® Immediate
Ayman A. Zayed, M.D., M.Sc., F.A.C.E., F.A.C.P. 15
Release Tablets at steady State in Adult Patients with Essential Hypertension, by Evaluating Heart
Rate Response to Bicycle Ergometry.
Principal Investigator (site) Protocol # SB-462795/002 (2005)
A Randomized, Single-Blind, Placebo-Controlled, Dose-Rising Study to Evaluate the Safety,
Tolerability, Pharmacokinetics and Preliminary Pharmacodynamics of Single and Repeat Oral Doses
of SB-462795 in Healthy Postmenopausal Women.
Principal Investigator (site) Protocol SYR-322-003 (2005)
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Comparison Study to Determine the
Efficacy and Safety of SYR110322 in Patients with Type 2 Diabetes, Who are Either Receiving No
Current Treatment or Currently Treated with Diet and Exercise, a Sulfonylurea, Metformin, or a
Combination of a Sulfonylurea and Metformin.
Sub-Investigator (site) Protocol CCOX189A2428 (2005)
A 4-week, multicenter, randomized, double-blind, double-dummy, parallel-group ambulatory blood
pressure monitoring studyto demonstrate that treatment with lumiacoxib 100 mg o.d. results in 24-
hour blood pressure profile superior to ibuprofen 600 mg t.i.d. in OA patients with controlled
hypertension.
Sub-Investigator (site) (Protocol 712753/007 & 00 (2005)
A randomized, double-blind trial to evaluate the efficacy and safety of fixed dose
{rosiglitazone/metformin} combination therapy compared to both rosiglitazone and metformin
monotherapies in drug naïve type 2 diabetes mellitus subjects.
Master Theses Supervision
Sep 2010-june 2011 “Impact Of Clinical Pharmacist Intervention On Health
Outcomes In Patients With Diabetes Mellitus”
By Mohammad khalaf dweib
Supervisors: Bulatova N.AbuRuz S. , Zayed A.A.
School of pharmacy, The University of Jordan.
March 2013-Present “The Association Between Apolipoprotein E Polymorphism
And Response To Statins In Jordanian Hyperlipidemic
Patients.”
By Rasha M. Mustafa
Supervisors : Gharayba M. , Zayed AA
School of medicine, The University of Jordan.
Achievements and Awards
1993 Resident Teacher of the Year Award
Medical Center of Central Massachusetts
Worchester, Massachusetts
USA
1993 In-training Examination in Internal Medicine, 100th Percentile
USA
1979 National Education Matriculate Examination
(97.3%) Ranked 7th of all Jordanians
Jordan
- Years in active
: From
To